The following is a target organ categorization of effects which may occur from exposure to hazardous chemicals including examples of signs and symptoms and.
What are the target organ of vinyl chloride.
For the oral route of exposure the primary target organ of vinyl chloride toxicity in animals is the liver.
When confined under high pressure in special containers vinyl chloride exists in a liquefied state.
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The target organs for vc now clearly in.
It is shipped and handled this way.
12 10 2017 01 identification of the substance preparation and the company undertaking product name vinyl chloride monomer sds no.
Table 1 target organs and potential effects of vinyl chloride exposure target organ effect.
Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body.
In 1974 vinyl chloride vc was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals.
Vinyl chloride monomer page 1 of 8 sds no.
Makarov et al 1984.
Synonyms trade names chloroethene chloroethylene ethylene monochloride monochloroethene monochloroethylene vc vcm vinyl chloride monomer vcm.
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Additional research has now demonstrated the carcinogenicity of vc to other organs and at lower concentrations.
The reader is referred to section 3 2 discussion of health effects by route of exposure for additional information on other effects.
There may be a latent period of hours to days between exposure and symptom onset.
The cns is the primary target of vinyl chloride acute toxicity.
Noncancerous hepatotoxicity and carcinogenicity of vinyl chloride are discussed in greater detail below.
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Target organ effect the target organs and potential effects of vinyl chloride exposure include.
About 13 billion kilograms are produced annually.
It has a faint sweet odor.
At room temperature vinyl chloride is a colorless highly flammable potentially explosive gas.
Toxins do not affect all organs in the body to the same extent due to their different cell structures.
Vinyl chloride is an organochloride with the formula h 2 c chcl that is also called vinyl chloride monomer vcm or chloroethene this colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride pvc.
The liver appears to be the most sensitive target organ of vinyl chloride.
The primary route of vinyl chloride exposure is inhalation.
The odor threshold for vinyl chloride is about 3 000 ppm in air depending on the individual.
Accidental ingestion may be possible when eating or smoking with contaminated hands.